up&up

Menopause Support

Serving

1 Tablet(s)

Form

tablet

UPC

756880543419

DSLD

20041

Avoid-flaggedObjective label signals

Flagged excipients

1 avoid · 4 caution

FDA recalls

no recall history

CAERS reports

FDA consumer events

Certifications

none recorded

1 avoid-level excipient · Every flag below links to the authority's published citation.

Supplement Facts

17 active ingredients

Ingredient	Amount	% DV
Vitamin D UNII · 9VU1KI44GP	1000 IU	250%
Vitamin E UNII · H4N855PNZ1	30 IU	100%
Thiamine ThiaminUNII · X66NSO3N35	5 mg	333%
Riboflavin UNII · TLM2976OFR	5 mg	294%
Niacin UNII · 2679MF687A	20 mg	100%
Vitamin B6 UNII · KV2JZ1BI6Z	20 mg	1000%
Folate UNII · 935E97BOY8	400 mcg	100%
Vitamin B12 UNII · 8406EY2OQA	25 mcg	417%
Calcium UNII · SY7Q814VUP	100 mg	10%
Phosphorus UNII · 27YLU75U4W	50 mg	5%
Selenium UNII · H6241UJ22B	70 mcg	100%
Chromium UNII · 0R0008Q3JB	120 mcg	100%
Black cohosh extract Black Cohosh	80 mg	—
Isoflavones isoflavone (unspecified)UNII · 71B37NR06D	80 mg	—
Estroblend(TM) Proprietary Blend (Herb/Botanical)	400 mg	—
Cranberry extract cranberryUNII · Y74M3X3345	300 mg	—
Boron UNII · N9E3X5056Q	1.5 mg	—

Flagged excipients

5 flagged · authority citations

● AVOIDTitanium Dioxide color
color
Banned in EU food products effective 2022-08 (Commission Regulation (EU) 2022/63) following EFSA Panel opinion that a safe daily intake could not be established due to genotoxicity concerns. Still GRAS in the US under 21 CFR 73.575 but EU position is stricter.
eur-lex.europa.eu →efsa.europa.eu →ecfr.gov →
◐ CAUTIONBlack Cohosh extract
other
LiverTox category C — plausible cause of acute liver injury based on 40+ published case reports. EMA HMPC monograph (2010) requires EU warning label. Still legal but FDA advisory encourages caution.
ncbi.nlm.nih.gov →ema.europa.eu →
◐ CAUTIONGreen Tea extract
other
EFSA 2018 scientific opinion: EGCG doses > 800 mg/day from supplements (not from beverage consumption) have been associated with hepatotoxic case reports. Capsule-form extracts pose higher risk than infused tea. LiverTox category B.
efsa.onlinelibrary.wiley.com →ncbi.nlm.nih.gov →
◐ CAUTIONFD&C Yellow #5 Lake
color
EU requires warning label 'may have an adverse effect on activity and attention in children' per Commission Regulation 1333/2008 Annex III (following Southampton study 2007). FDA requires specific label declaration (21 CFR 74.705).
eur-lex.europa.eu →ecfr.gov →
◐ CAUTIONFD&C Red #40 Lake
color
EU requires the same 'attention/activity in children' warning label as Yellow 5 per Commission Regulation 1333/2008 Annex III. California enacted a public-school ban effective 2028 (AB 2316, 2024).
eur-lex.europa.eu →leginfo.legislature.ca.gov →

Other ingredients

Dicalcium Phosphate · Non-GMO Kudzu Extract · Cellulose · Calcium Carbonate · Croscarmellose · Crospovidone · Boron Amino Acid Chelate · D-Alpha-Tocopheryl Acid Succinate · Pyridoxine Hydrochloride · Cranberry Extract · Polyvinyl Alcohol · Niacinamide · Silicon Dioxide · Stearic Acid · Polyethylene Glycol · Magnesium Silicate · Sodium Selenate · Thiamine Mononitrate · Vegetable Magnesium Stearate · Riboflavin · Magnolia bark powder · Starch · Non-GMO Soy Extract · Chromium Amino Acid Chelate · Date seed extract · Cinnamon extract · Folic Acid · Polysorbate 80 · Cyanocobalamin · Cholecalciferol