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Irwin Naturals

EstroPause

Serving
2 Liquid Softgel(s)
Per container
20
Form
capsule-unknown
UPC
710363262440
DSLD
292070
Formula hash
0c40b60d2ed1
Brand context
Irwin Naturals
Catalog
314
products
With avoid flag
269
products
FDA recalls
0
history
CAERS
12
reports
Avoid-flaggedObjective label signals
Flagged excipients
1
1 avoid · 0 caution
FDA recalls
0
no recall history
CAERS reports
11
FDA consumer events
Certifications
0
none recorded
1 avoid-level excipient · Every flag below links to the authority's published citation.
NIH LiverTox
2 ingredients with hepatotoxicity classification
Worst severity: Category C
About LiverTox →
  • Black CohoshCategory C

    LiverTox Category C. 40+ published case reports of acute liver injury. EMA HMPC 2010 monograph requires warning label in EU. FDA advisory encourages caution.

    LiverTox →
  • St. John's WortCategory D

    LiverTox Category D. Few case reports of hepatitis; causality uncertain. Major drug-interaction concern (CYP3A4 induction) — can reduce levels of warfarin, oral contraceptives, immunosuppressants, HIV antivirals.

    LiverTox →

Supplement Facts

17 active ingredients
IngredientAmount% DV
Calories
otherUNII · 1
35 Calorie(s)—
Total Fat
Fat (unspecified)other
2 Gram(s)3%
Cholesterol
otherUNII · 97C5T2UQ7J
10 mg3%
Total Carbohydrates
CarbohydrateotherUNII · 0
2 Gram(s)1%
Protein
Protein (unspecified)other
2 Gram(s)—
Calcium
mineralUNII · SY7Q814VUP
UL · set6 effects
500 mg38%
Iron
mineralUNII · E1UOL152H7
UL · set5 effects
0.6 mg3%
Magnesium
mineralUNII · I38ZP9992A
UL · set6 effects
200 mg48%
Sodium
mineralUNII · 9NEZ333N27
15 mg1%
Fish Oil
otherUNII · XGF7L72M0F
2158 mg—
St. John's Wort extract
St. John's WortherbUNII · UFH8805FKA
LiverTox D
300 mg—
Soy Isoflavones
isoflavone (unspecified)herbUNII · 71B37NR06D
100 mg—
Black Cohosh Root Extract
Black CohoshherbUNII · K73E24S6X9
LiverTox C
80 mg—
Red clover powder
Red CloverherbUNII · L9153EKV2Y
40 mg—
Asian Ginseng Root Extract
Oriental GinsengherbUNII · CUQ3A77YXI
31 mg—
Chaste Tree
ChastetreeherbUNII · 433OSF3U8A
20 mg—
BioPerine Complex
Proprietary Blendother
6 mg—
What this product supports · authorized claims

13 authority-backed effects

Rolled up from EFSA / FDA / NIH ODS authorized function claims on this product's active ingredients. Each row shows which ingredients contribute.

Flagged excipients

1 flagged · authority citations

  • ● AVOIDTitanium Dioxide
    color

    Banned in EU food products effective 2022-08 (Commission Regulation (EU) 2022/63) following EFSA Panel opinion that a safe daily intake could not be established due to genotoxicity concerns. Still GRAS in the US under 21 CFR 73.575 but EU position is stricter.

    eur-lex.europa.eu →efsa.europa.eu →ecfr.gov →
FDA CAERS · adverse event context
11
consumer-submitted adverse event reports filed with the FDA CFSAN Adverse Event Reporting System mentioning this product or its brand.

CAERS reports are unverified consumer submissions — not adjudicated causality. Large well-known brands accumulate proportionally more reports simply due to broader use. About CAERS →

Other ingredients

Gelatin · Water, Purified · Glycerin · Soy Lecithin · Beeswax · Lycopene · Maltodextrin